Epithelial cells provide an initial line of defense against damage and pathogens in barrier tissues such as the skin; however this balance is disrupted in obesity and metabolic disease. Skin gamma de
*p-values determined using Mann–Whitney U-tests. Subsets of CD4+ T cells are presented as median (interquartile range) absolute cells/μL and defined as gut homing: α4+β7+, homing activated: α4+7+CD25+
