Crystal structure of HIV-1 protease in complex with lactam derivative 2
收藏Protein Data Bank Japan2023-11-29 更新2026-03-28 收录
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Crystal structure of HIV-1 protease in complex with lactam derivative 2 Descriptor: (3~{R},4~{R})-1-[(4-methoxyphenyl)methyl]-3-(3-methylbutyl)-3-[4-methylsulfonyl-2-[(2~{S})-1-oxidanylpropan-2-yl]oxy-phenyl]-4-oxidanyl-pyrrolidin-2-one, GLYCEROL, Protease Authors: Kojima, E, Iimuro, A, Nakajima, M, Kinuta, H, Asada, N, Sako, Y, Nakata, Z, Uemura, K, Arita, S, Miki, S, Wakabayashi-Morimoto, C, Tachibana, Y, Fumoto, M. Deposit date: 2021-12-17 Release date: 2022-11-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Pocket-to-Lead: Structure-Based De Novo Design of Novel Non-peptidic HIV-1 Protease Inhibitors Using the Ligand Binding Pocket as a Template. J.Med.Chem., 65, 2022
创建时间：
2021-12-17
