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Crystal structure of HCV NS3/4A D168A protease in complex with CH-24

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of HCV NS3/4A D168A protease in complex with CH-24 Descriptor: 1,2-ETHANEDIOL, NS3/4A protease, SULFATE ION, ... Authors: Zephyr, J, Schiffer, C.A. Deposit date: 2020-12-29 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants. J.Med.Chem., 64, 2021

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2020-12-29
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