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Crystal structure of scFv ATOR 1017 bound to human 4-1BB

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Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
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Crystal structure of scFv ATOR 1017 bound to human 4-1BB Descriptor: Single chain Fv, Tumor necrosis factor receptor superfamily member 9 Authors: Hakansson, M, Von Schantz, L, Rose, N. Deposit date: 2023-05-08 Release date: 2024-03-13 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.1 Å) Cite: ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1. Cancer Immunol.Immunother., 72, 2023

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2023-05-08
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