Dermal collagen fiber data for Fiber Classification by ResNet
收藏DataCite Commons2025-06-01 更新2025-06-15 收录
下载链接:
https://datadryad.org/dataset/doi:10.5061/dryad.6q573n66z
下载链接
链接失效反馈官方服务:
资源简介:
Type I collagen is a major component of the dermis and is formed by dermal
fibroblasts. The development of dermal collagen structures has not been
fully elucidated despite the major presence and importance of the dermis.
This Lack of understanding is due in part to the opacity of mammalian skin
and it has been an obstacle to cosmetic and medical developments. We
succeeded in revealing the process of dermal collagen formation using the
highly transparent skin of the axolotl and fluorescent collagen probes. We
clarified that epidermal cells, not dermal fibroblasts, primarily
contribute to dermal collagen formation. Fibroblasts play a role in
modifying the collagen fibers already built by keratinocytes. We confirmed
that collagen production by keratinocytes is a widely conserved mechanism
in other model organisms. Our findings demand the current consensus about
dermal collagen formation to change and lead to innovations in cosmetology
and skin medication.
提供机构:
Dryad
创建时间:
2025-01-28



