Literature Values for Km and Vmax for the WT Human αGal.

Note. The values given are for the human enzyme purified directly from human tissues or from the indicated recombinant sources. Replagal is produced in human foreskin fibroblasts and Fabrazyme is produced in CHO cells. The average from these literature values are 2.6 ± 0.9mM (Km) and 3.2 ± 1.1mmole/hr/mg (Vmax). NA: not available. MUG was used as the substrate to determine the Km and Vmax values.Literature Values for Km and Vmax for the WT Human αGal.