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Bile acid receptor FXR promotes intestinal epithelial ferroptosis and subsequent ILC3 dysfunction in neonatal necrotizing enterocolitis [scRNA-seq]

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NIAID Data Ecosystem2026-05-02 收录
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We performed scRNA-seq to analyze the changes of IECs cell subsets and signaling pathways in neonatal mice after NEC IECs (EpCAM+CD45-) from Ctrl pups, NEC pups, Fxrfl/fl and FxrΔIEC NEC pups were sorted via BD FACS. Sorted cells were sequenced using the 10x Genomics platform.

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2025-02-07
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