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Neosartoryadins A and B, Fumiquinazoline Alkaloids from a Mangrove-Derived Fungus Neosartorya udagawae HDN13-313

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Figshare2016-02-12 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Neosartoryadins_A_and_B_Fumiquinazoline_Alkaloids_from_a_Mangrove_Derived_Fungus_i_Neosartorya_udagawae_i_HDN13_313/2087449
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Neosartoryadins A (1) and B (2), both with a unique 6/6/6/5 quinazoline ring system connected directly to a 6/5/5 imidazoindolone ring, together with three biogenetically related compounds 3–5, were isolated from the endophytic fungus Neosartorya udagawae HDN13-313. The absolute configurations of new compounds 1–4 were established. Compounds 1 and 2 displayed anti-influenza virus A (H1N1) activities with IC50 values of 66 and 58 μM, respectively (ribavirin as positive control, IC50 = 94 μM).
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2016-02-12
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