The Cancer Genome Atlas Lung Adenocarcinoma Collection (TCGA-LUAD)

The Cancer Genome Atlas Lung Adenocarcinoma (TCGA-LUAD) data collection is part of a larger effort to build a research community focused on connecting cancer phenotypes to genotypes by providing clinical images matched to subjects from The Cancer Genome Atlas (TCGA). Clinical, genetic, and pathological data resides in the Genomic Data Commons (GDC) Data Portal while the radiological data is stored on The Cancer Imaging Archive (TCIA). Matched TCGA patient identifiers allow researchers to explore the TCGA/TCIA databases for correlations between tissue genotype, radiological phenotype and patient outcomes. Tissues for TCGA were collected from many sites all over the world in order to reach their accrual targets, usually around 500 specimens per cancer type. For this reason the image data sets are also extremely heterogeneous in terms of scanner modalities, manufacturers and acquisition protocols. In most cases the images were acquired as part of routine care and not as part of a controlled research study or clinical trial.癌症基因组图谱肺腺癌（TCGA-LUAD）数据集是一项更大规模研究计划的组成部分，该计划旨在构建一个研究共同体，通过为癌症基因组图谱（TCGA）的受试者匹配临床影像，将癌症表型与基因型建立关联。临床、遗传与病理数据存储于基因组数据共享平台（GDC）数据门户，而放射影像数据则归档于癌症影像档案库（TCIA）。匹配的TCGA患者标识符可帮助研究人员在TCGA与TCIA数据库中探索组织基因型、放射影像表型与患者预后之间的相关性。TCGA的组织样本采集自全球众多站点，以达成每种癌症类型约500份标本的入组目标。正因如此，该影像数据集在扫描模态、设备制造商及采集协议方面均呈现出极强的异质性。在大多数情况下，这些影像均采集自常规诊疗流程，而非受控研究或临床试验的一部分。