Ribosomal movement impeded at a pseudoknot required for frameshifting.
收藏PubMed Central1992-09-15 更新2026-05-16 收录
下载链接：
https://pmc.ncbi.nlm.nih.gov/articles/PMC49975/
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资源简介：
Translational frameshifting sometimes occurs when ribosomes encounter a "shift" site preceding a region of unusual secondary structure, which in at least three cases is known to be a pseudoknot. We provide evidence that ribosomes have a decreased rate of movement through a pseudoknot required for frameshifting. These paused ribosomes are directly situated over the shift sequence. Ribosomal pausing appears to be necessary but not sufficient for frameshifting. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1992-09-15
