CpKRS complexed with lysine and an inhibitor
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CpKRS complexed with lysine and an inhibitor Descriptor: 2-azanyl-4-(trifluoromethyl)-6-[[(1~{R},3~{S})-3-(trifluoromethyl)cyclohexyl]methyl]-7~{H}-pyrrolo[3,4-d]pyrimidin-5-one, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Dawson, A, Baragana, B, Caldwell, N. Deposit date: 2023-11-03 Release date: 2024-10-30 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy. Sci Transl Med, 16, 2024
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2023-11-03



