Excitatory SST neurons in the medial paralemniscal nucleus control repetitive self-grooming and encode reward

We revealed that the MPLSST neurons are excitatory neurons releasing neurotransmitter glutamate,and reveal that more than half of these neurons co-release neuropeptides SST and PTH2 We performed a spatial transcriptomics analysis using the 10x Genomics Visium platform seeking to profile potentially informative markers in the MPL from a coronal section (close to bregma -4.72 mm) from post-natal day 60 (P60) male mice本研究明确了MPLST神经元为释放神经递质谷氨酸（glutamate）的兴奋性神经元，并证实该类神经元中超过半数可共分泌神经肽SST与PTH2。我们采用10x Genomics Visium平台开展空间转录组分析，旨在对出生后第60天（P60）雄性小鼠的、靠近前囟点（bregma）-4.72 mm的冠状脑切片中的MPL区域的潜在信息标记物进行表达谱分析。