Transcriptome of juvenile zebrafish treated with the aromatase inhibitor exemestane and solvent control

To reveal the transcriptomic changes during the sex differetiation in larval zebrafish, we treated the lavarl fish with aromatase inhibitors (EM, CAS: 107868-30-4, 100 µg/L), as well as solvent as a control, and sampled them after the exposure. Overall design: PolyA+ RNA-seq were performed on 6 samples, each of which was a mixture of 25 juvenile zebrafish. There are twor groups of larval zebrafish were exposed for two exposure treatments. Each group contained 3 replicates, with 25 fish per replicate. The exposure treatments included (1) DMSO (10 µL/L), (2) EM + DMSO. The exposure periods were 32 days for zebrafish.