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Phosphoryl Azides as Versatile New Reaction Partners in the Cu-Catalyzed Three-Component Couplings

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NIAID Data Ecosystem2026-03-06 收录
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Phosphoryl azide was successfully employed as an efficient reacting partner in the Cu-catalyzed three-component reaction with 1-alkynes and amines to produce the corresponding phosphoryl amidines in high yields. A range of fruitful applicability of the produced amidines was also demonstrated such as an alkoxide exchange and asymmetric α-alkylation of optically active BINOL-derived amidines.

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2007-12-07
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