首页/数据集/Oct4-mediated inhibition of Lsd1 activity promotes the active and primed state of pluripotency enhancers

Oct4-mediated inhibition of Lsd1 activity promotes the active and primed state of pluripotency enhancers

NIAID Data Ecosystem2026-03-11 收录

干细胞多能性调控

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数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE135227 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2020-06-29

干细胞多能性调控

iPSC重编程

Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main mul

NIAID Data Ecosystem140

H3K9me3 and H3K27me3 ChIP-Seq in retinoblastoma 1 (RB1) knock out cells

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RB1基因

Comparative analysis of H3K9me3 and H3K27me3 in RB1 KO and wild type IMR-90 cells Overall design: Examination of 2 histone modifications in RB1 KO and wild type IMR-90 cells

NIAID Data Ecosystem70

Crystal structure of the TAL effector dHax3 bound to methylated dsDNA

DNA复合物

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Crystal structure of the TAL effector dHax3 bound to methylated dsDNA Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P

Protein Data Bank Japan2023-11-08 更新40

Microcystin-LR induces lactate production disruption via altering the m6A modification in Sertoli cells

毒性代谢

表观遗传修饰

The differentially expressed genes were shown in the Data-Fig2A. Other data (qRT-PCR, western blot, Elisa, etc.) was shown in the Data-sheet1.

NIAID Data Ecosystem80

Geminin Is Required for the Maintenance of Pluripotency

干细胞多能性调控

转录因子网络

Pluripotency requires the expression of the three core transcriptions factors Oct4, Sox2 and Nanog, as well as further, complementary proteins. The geminin protein is part of this network, and was sho

Figshare2016-01-18 更新70

Oct4-mediated inhibition of Lsd1 activity promotes the active and primed state of pluripotency enhancers

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