SERBP1-RIP-Seq on mouse

Dysregulation of pain-related genes caused by nerve injury leads to the development of neuropathic pain and its comorbid anxiety. The hind limb region of the primary somatosensory cortex (S1HL) is a key brain area for the generation and maintenance of pain. To investigate changes in the levels of SERBP1-bound mRNAs within the S1HL region under neuropathic pain conditions, we employed SERBP1 RNA immunoprecipitation sequencing (SERBP1-RIP-Seq).