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Somatic haploidization using mature oocytes in mice
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2022-01-03
相关数据集
Identification of differential expressed genes among reprogrammed cells cultured under control condition and calcineurin-NFAT pathway inhibition condition at reprogramming day 3 and day 6 through genome-wide transcript profiling
Inhibition of calcineurin-NFAT pathway at the early stage can block somatic cell reprogramming. In order to study how the calcineurin-NFAT pathway contributes to the early stage of reprogramming, we d
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Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming
Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming
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Expresion and methylation analysis of adult somatic cell lines, five days after OSK, AOX15 and AO9 overxpression and derived iPSC using the different combinations. Expresion and methylation analysis of adult somatic cell lines, five days after OSK, AOX15 and AO9 overxpression and derived iPSC using the different combinations
Methods of reprogramming somatic cells to an induced pluripotent state (iPSC) have enabled the direct modeling of human disease and ultimately promise to revolutionize regenerative medicine. iPSCs off
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Additional file 7: of Sirt6 regulates efficiency of mouse somatic reprogramming and maintenance of pluripotency
Table S3. Differential expression genes in Sirt6-null MEFs relative to wild-type controls. (XLSX 97 kb)
Figshare2019-01-11 更新20
Generation of functional rat spermatozoa in sterile mice utilizing blastocyst complementation with pluripotent stem cells [scRNAseq_rat]
Pluripotent stem cells (PSCs) provide a powerful tool to produce transgenic animals for biomedical research. However, impaired PSC contribution to chimerism and most notably to the germline oftentimes
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