Small Molecule inhibitors of IAP
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Small Molecule inhibitors of IAP Descriptor: 1-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2~{H}-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2~{R},5~{R})-5-methyl-2-[[(3~{R})-3-methylmorpholin-4-yl]methyl]piperazin-4-ium-1-yl]ethanone, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... Authors: Williams, P.A. Deposit date: 2016-10-25 Release date: 2017-05-24 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP). J. Med. Chem., 60, 2017
创建时间:
2016-10-25



