Interaction analyses between the DIO2 rs225017 (T/A) and rs225014 (Thr92Ala) polymorphisms according to fasting plasma insulin and HOMA-IR index.

Data are mean ± SD, median (minimum - maximum values) or %. BMI, body mass index; HOMA-IR, homeostasis model assessment - insulin resistance; Met, metformin; SU, sulfonylureas.aData were analyzed using the Student t test or χ2, as appropriate.bF and P values obtained from the general linear model-interaction analyses, after adjusting for age, sex, BMI and use of medication for T2DM.cVariables which were logarithmically transformed before analyses.dAdjusted R squared for fasting plasma insulin = 0.135.eAdjusted R squared for HOMA-IR = 0.111.