BIOGRID CURATED DATA FOR PCT1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for PCT1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Cholinephosphate cytidylyltransferase; a rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding; contains an element within the regulatory domain involved in both silencing and activation of enzymatic activity

由BioGRID（https://thebiogrid.org）精心编纂的PCT1（酿酒酵母S288c）蛋白质-蛋白质、遗传以及化学相互作用数据集；定义：胆碱磷酸胞苷转移酶；磷脂酰胆碱合成途径中决定速率的酶，由Sec14p抑制，脂质结合后激活；调控域内含有参与酶活性沉默和激活的元素。