Nickel-Catalyzed Reductive Coupling of Aryl Bromides with Tertiary Alkyl Halides
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https://figshare.com/articles/dataset/Nickel_Catalyzed_Reductive_Coupling_of_Aryl_Bromides_with_Tertiary_Alkyl_Halides/2131285
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资源简介：
A mild Ni-catalyzed
reductive arylation of tertiary alkyl halides
with aryl bromides has been developed that delivers products bearing
all-carbon quaternary centers in moderate to excellent yields with
excellent functional group tolerance. Electron-deficient arenes are
generally more effective in inhibiting alkyl isomerization. The reactions
proceed successfully with pyridine or 4-(dimethylamino)pyridine, while
imidazolium salts slightly enhance the coupling efficiency.
创建时间：
2016-02-13
