Room temperature X-ray crystallography reveals catalytic cysteine in the SARS-CoV-2 3CL Mpro is highly reactive: Insights for enzyme mechanism and drug design
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Room temperature X-ray crystallography reveals catalytic cysteine in the SARS-CoV-2 3CL Mpro is highly reactive: Insights for enzyme mechanism and drug design Descriptor: 1-ETHYL-PYRROLIDINE-2,5-DIONE, 3C-like proteinase Authors: Kneller, D.W, Kovalevsky, A, Coates, L. Deposit date: 2020-06-05 Release date: 2020-06-17 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M pro : insights into enzyme mechanism and drug design. Iucrj, 7, 2020
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2020-06-05
