Sebocyte TLR Response

NIAID Data Ecosystem2026-05-25 收录

皮脂腺细胞免疫反应

痤疮分子机制

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP151073 数据链接链接失效反馈

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资源简介：

Measuring the response of human sebocytes (SEB-1) to the Toll-like Receptor 2/6 ligand (MALP-2) following treatment with siRNA specific for HDAC8 and HDAC9 or negative control. Comparing the transcriptome of sebocytes with clinical acne lesion.

创建时间：

2018-06-22

Resveratrol ameliorates lipid accumulation and inflammation in human SZ95 sebocytes via the AMPK signaling pathways in vitro

痤疮分子机制

AMPK信号通路

Background: Acne Vulgaris is one of the commonest dermatological challenges lacking effective and well-tolerated treatment. An earlier study indicated that resveratrol (RVT) exhibits therapeutic effec

NIAID Data Ecosystem90

Single cell RNA-seq data comparing lesional (papules) and non-lesional skin biopsies of acne patients. Single cell RNA-seq data comparing lesional (papules) and non-lesional skin biopsies of acne patients

痤疮分子机制

单细胞转录组学

We performed single-cell RNA seq analysis on skin biopsies from six acne patients with a total of 32,966 cells from lesional skin and 29,202 cells from non-lesional skin using 10X Genomics. Gene expre

NIAID Data Ecosystem30

Acne flare-up in treatment process: investigating the difference of gene expression in peripheral blood. Acne flare-up in treatment process: investigating the difference of gene expression in peripheral blood

痤疮分子机制

免疫炎症基因组学

Objectives: To identify gene expression changes in acne flare-up patients, thereby exploring the mechanisms of acne flare-up after treatment. Methods: 11 acne patients and 3 healthy people were divide

NIAID Data Ecosystem10

Microarray profiling of circRNA-associated-ceRNA networks in acne lesions. Microarray profiling of circRNA-associated-ceRNA networks in acne lesions

痤疮分子机制

circRNA调控

To investigate the differential expression of circRNA in severe acne and its role in competitive endogenous RNA regulatory networks, we have employed RNA microarray technology as a discovery platform

NIAID Data Ecosystem50

Expression at the mRNA level of antimicrobial peptides in the German acne cohort determined by Affymetrix microarray technology.

痤疮分子机制

抗菌肽表达

Expression at the mRNA level of antimicrobial peptides in the German acne cohort determined by Affymetrix microarray technology.

NIAID Data Ecosystem30