Data from: Genome-wide association study for body weight in cattle populations from Siberia

Body weight is a complex trait in cattle associated with commonly used
commercial breeding measurements related to growth. Although many
quantitative trait loci (QTL) for body weight have been identified in
cattle so far, searching for genetic determinants in different breeds or
environments is promising. Therefore, we carried out a genome‐wide
association study (GWAS) in two cattle populations from the Russian
Federation (Siberian region) using the GGP HD150K array containing 139 376
single nucleotide polymorphism (SNP) markers. Association tests for 107
550 SNPs left after filtering revealed five statistically significant SNPs
on BTA5, considering a false discovery rate of less than 0.05. The
chromosomal region containing these five SNPs contains the CCND2 gene,
which was previously associated with average daily weight gain and body
mass index in US beef cattle populations and in humans respectively. Our
study is the first GWAS for body weight in beef cattle populations from
the Russian Federation. The results provided here suggest that, despite
the existence of breed‐ and species‐specific QTL, the genetic architecture
of body weight could be evolutionarily conserved in mammals.