SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression [ChIP-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP371540
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资源简介:
We have found that loss of SMNDC1 (Survival Motor Neuron Domain Containing 1), a component of the spliceosome complex, in both murine alpha cells and human islets is capable of inducing an overall increase in beta cell markers and activating insulin transcription. Overall design: H3K9me3 ChIP-seqs in alphaTC1 cells (murine alpha cell line) 5 days after transduction with an Smndc1 shRNA and in betaTC3 cells (murine beta cell line).
创建时间:
2022-07-02



