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Gut Microbiome Changes by Anti-PD-L1 Antibody and/or 17b-Estradiol Treatment in MC38 Colon Tumor Model

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NIAID Data Ecosystem2026-05-02 收录
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We hypothesized that the gut microbiome composition in a syngeneic CRC mouse model could be regulated under various conditions, such as sex, anti-PD-L1 antibody or E2 treatment. To verify this hypothesis, this study focused to investigate the gut microbiome as a potential biomarker regulated by anti-PD-L1 antibodies and/or E2 in the MC38 colon cancer mouse model.

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2025-07-23
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