Recent studies have highlighted the importance of interconnectivity in a large range of molecular and human disease-related systems. Network medicine has emerged as a new paradigm to deal with complex
Protein-protein interactions are an important mechanism for the regulation of enzyme function allowing metabolite channeling, crosstalk between pathways or the introduction of post-translational modif
1(includes reciprocal interactions). Topological parameters for T. pallidum protein datasets and corresponding networks were calculated using the NetAnalyzer plugin for Cytoscape (http://med.bioinf.mp
P311 is a highly conserved multifunctional protein. However, it does not belong to any established family of proteins, and its biological function has not been entirely determined. This study aims to