MDR Efflux in Cisplatin-Naive and Cisplatin-Exposed A2780 Ovarian Cancer Cells Responds Differently to Cell Culture Dimensionality - SI
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contains image stacks of monolayers formed by the drug-naïve (T stacks 1, 2)
and drug-exposed cells (T stacks 3, 4), as well as image stacks of spheroids
formed by the drug-naive (ZT stacks 1–6) and drug-exposed (ZT stacks 7-11) cells.
Image stacks were used for extraction of kinetic traces utilized subsequently for
the building kinetic cytometry histograms. Different T stacks and different ZT
stack correspond to experiments performed on different days with new samples.
Kinetic
traces of individual spheroid and monolayer cells obtained from time dependence
of fluorescence intensity calculated from the image stacks.
Kinetic
cytometry histograms: kMDR distributions in populations of spheroid
and monolayer cells. The number of cells in each histogram is 347.
创建时间:
2020-09-24



