five

Whsc1 controls mesendodermal transcription factor expression

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP185990
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We report here chromatin related factor Whsc1 links pluripotency exit and mesendodermal differentiation. We performed RNA-seqs to compare Whsc1+/+ and Whsc1-/- embryonic stem cells (ESCs) to compare the transcriptomes. UMI-4C experiments have been performed to identify regions having contacts with promoter regions of downstream Whsc1 targets: the mesendoderm transcritpion factors Overall design: RNA-seq in Whsc1+/+ and Whsc1-/- ESCs. UMI-4C in Whsc1+/+ and Whsc1-/- ESCs compared to D6 Whsc1+/+ and Whsc1-/- embryoid bodies (Ebs).
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2019-09-24
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