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T cell intrinsic immunomodulatory effects of TAK-981 in chronic lymphocytic leukemia patient derived T cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE209744
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Transcriptome analysis of TAK981 or DMSO pre-treated chronic lymphocytic leukemia patient derived T cells upon TCR engagement Peripheral blood derived and FACS sorted (CD4+CD45RA+ CD45RO-) Naïve CD4 T cells from four chronic lymphocytic leukemia patients was pre treated with TAK981 or DMSO (1hr) then stimulated with CD3/CD28. Gene expression profiles were determined through use of Affymetrix Clariom S hybridization array. Gene expression was quantified by Transcriptome Analysis Console (v 4.0) software. No technical replicates were performed.
创建时间:
2024-07-25
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