Comparison of loop modeling results on the test set of template-based models.

The average RMSD and its standard deviation are reported in Å. The Loop RMSD is calculated as the root-mean-square deviation of the main-chain atoms N, Cα, C, and O.1)Loop conformations generated by MODELLER [30].2)Loop conformations generated by loop refinement using ModLoop of MODELLER [1], [27].3)Results of the best-score models sampled by Next-generation KIC (NGK) using the protocol provided by Stein et al.[18].500 models were generated for each target as in Stein et al. The Rosetta program v3.5 was used.4)Loop set constructed in this study. See Table S7 for the list of loops.Comparison of loop modeling results on the test set of template-based models.