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Low- and High-Grade Mucoepidermoid Carcinomas have different genomic profiles and CRTC1-MAML2 Fusion Gene Status

ChEBI2012-12-31 更新2026-07-21 收录

黏液表皮样癌基因组学

肿瘤基因融合

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36282 数据链接链接失效反馈

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Low- and High-Grade Mucoepidermoid Carcinomas have different genomic profiles and CRTC1-MAML2 Fusion Gene Status

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创建时间：

2012-12-31

肿瘤基因融合

转录组生物信息学分析

Whole transcriptome sequencing was used to study a small round cell tumor in which a t(4;19)(q35;q13) was part of the complex karyotype but where the initial reverse transcriptase PCR (RT-PCR) examina

NIAID Data Ecosystem50

Ewings Sarcoma RNA-Seq

尤文肉瘤基因组学

肿瘤基因融合

Sarcomas are cancers of the bone and soft tissue often defined by their gene fusions. However, the timing, context, and processes by which these pathogenic fusions arise are unknown. We explored this

NIAID Data Ecosystem30

NTRK1 Fusion in Glioblastoma Multiforme

肿瘤基因融合

疾病靶点发现

Glioblastoma multiforme (GBM) is the most aggressive form of brain tumor, yet with no targeted therapy with substantial survival benefit. Recent studies on solid tumors showed that fusion genes often

Figshare2016-01-18 更新20

Genome-wide identification of oncogenic fusions in lung cancer by functional translocation sequencing. Genome-wide identification of oncogenic fusions in lung cancer by functional translocation sequencing

肿瘤基因融合

化疗耐药机制

Fusions involving tyrosine kinases are oncogenic drivers in lung cancer and other solid tumors but also mediate resistance to targeted therapy. Despite gene rearrangements involving tyrosine kinases t

NIAID Data Ecosystem30

BPDCN MYB Fusions Regulate Cell Cycle Genes, Impair Differentiation and Induce Myeloid-Dendritic Cell Leukemia [HoxRNASeq]. BPDCN MYB Fusions Regulate Cell Cycle Genes, Impair Differentiation and Induce Myeloid-Dendritic Cell Leukemia [HoxRNASeq]

白血病分子机制

肿瘤基因融合

MYB fusions are recurrently found in select cancers, including blastic plasmacytoid dendritic cell neoplasm (BPDCN), an acute leukemia with poor prognosis. They are markedly enriched in BPDCN compared

NIAID Data Ecosystem20

Low- and High-Grade Mucoepidermoid Carcinomas have different genomic profiles and CRTC1-MAML2 Fusion Gene Status

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