Crystal structure of XIAP-Bir2 with a bound benzodiazepinone inhibitor.
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of XIAP-Bir2 with a bound benzodiazepinone inhibitor. Descriptor: E3 ubiquitin-protein ligase XIAP, N-{(3S)-5-(4-aminobenzoyl)-1-[(2-methoxynaphthalen-1-yl)methyl]-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl}-N~2~-methyl-L-alaninamide, ZINC ION Authors: Lukacs, C.M, Janson, C.A. Deposit date: 2013-05-03 Release date: 2013-11-27 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain. J.Med.Chem., 56, 2013
创建时间：
2013-05-03
