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Glucose Starvation Induces a Switch in the Histone Acetylome for Activation of Gluconeogenic and Fat Metabolism Genes

NIAID Data Ecosystem2026-03-13 收录

代谢表观遗传学

糖异生基因调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE178161 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2022-04-07

染色质可及性分析

代谢表观遗传学

Male C57BL/6 mice, sourced from the Jackson Laboratory, were acquired at 12 weeks of age. The mice were housed in groups of three per cage, with unrestricted access to water and a standard chow diet.

NIAID Data Ecosystem70

Brain histone beta-hydroxy-butirylation couples metabolism with gene expression (ChIP-seq). Brain histone beta-hydroxy-butirylation couples metabolism with gene expression (ChIP-seq)

组蛋白β-羟基丁酰化

代谢表观遗传学

We report changes in beta-hydroxybutyrylation of lysine (K) 9 on histone H3 in the occipital cortex of mice after 48 hour fasting. Overall design: ChIP-seq of H3 K9 beta-hydroxybutyrylation in the occ

NIAID Data Ecosystem50

Kmt5a Controls Hepatic Metabolic Pathways by Facilitating RNA Pol II Release from Promoter-Proximal Regions. Mus musculus

代谢表观遗传学

RNA聚合酶II释放机制

H4K20 monomethylation maintains genome integrity by regulating proper mitotic condensation, DNA damage response and replication licensing. Here we show that in non-dividing hepatic cells H4K20Me1 is s

NIAID Data Ecosystem30

MiRNA expression alternations in the offspring liver from chromium restriction diet dams

母体营养编程

代谢表观遗传学

Maternal chromium restriction may disturb susceptibility in offspring. Liver from maternal chromium diet has 8 up- and 6 down- regulated miRNAs, compared to control. We performed miRNA array analyses

NIAID Data Ecosystem50

Statistic of RNA-seq DEGs.

代谢表观遗传学

性二态性基因调控

Little is known about how sex and diet interact at the level of chromatin organization. A comprehensive analysis of diet-induced chromatin dynamics can reveal how the liver mounts a rapid adaptive res

NIAID Data Ecosystem30

Glucose Starvation Induces a Switch in the Histone Acetylome for Activation of Gluconeogenic and Fat Metabolism Genes

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