Discovery of a high affinity inhibitor of cGAS
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Discovery of a high affinity inhibitor of cGAS Descriptor: 5-phenyltetrazolo[1,5-a]pyrimidin-7-ol, Cyclic GMP-AMP synthase, ZINC ION Authors: Hall, J. Deposit date: 2017-03-22 Release date: 2017-09-27 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS ONE, 12, 2017
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2017-03-22
