The effects of STI-associated urethritis on the establishment and maintenance of compartmentalized HIV-1 in the male genital tract

An analysis of HIV-1 V1/V3 envelope sequences derived from the blood and semen of men with and without STI-associated urethritis. The goal of the study was to determine whether inflammation related to STI-associated urethritis impacted the formation and/or maintenance of genetically diverse, compartmentalized lineages in the genital tract.