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A,D-<i>seco</i>-Limonoids from the Stems of <i>Clausena emarginata</i>

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NIAID Data Ecosystem2026-03-08 收录
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Twelve new A,D-seco-limonoids, clauemargines A–L (1–12), and three known analogues were isolated from the stems of Clausena emarginata. The absolute configurations of 1 and 5 were confirmed by X-ray crystallography and ECD spectroscopy, respectively. Compounds 1, 2, 8–10, and 13 showed moderate inhibitory effects on LPS-induced NO production (IC50 values < 10 μM).

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2016-02-17
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