Multi-ancestry maternal GWAS summary statistics from "Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects"

Maternal henotypes analysed: 1-hour glucose post-OGTT (1h_Glucose), 2-hour glucose post-OGTT (2h_Glucose), fasting glucose (FG), gestational diabetes mellitus (GDM), and glycated haemoglobin (HbA1c). Quality control prior to the meta-analysis excluded SNVs with poor imputation quality (r² < 0.3 or info < 0.4), minor allele count < 10, and/or effect allele frequency < 0.1%; genetic data were lifted over to GRCh38 where required. Multi-ancestry maternal meta-analyses used MR-MEGA including three principal components; summary statistics are provided for all populations combined (FG n = 55,371; 1hG n = 38,439; 2hG n = 46,401; HbA1c n = 9,724; GDM n = 814,450 [38,305 cases]), filtered at MAF ≥ 0.01 with SNPs removed if absent from ≥ 50% of the sample. For further details on sample sizes, analytical pipelines, and cohort-specific QC procedures, see Supplementary Materials.