five

Picking the right target for HSC-mediated gene therapy

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NIAID Data Ecosystem2026-03-10 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA433002
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Hematopoietic stem cell (HSC)-mediated gene therapy holds enormous potential for the treatment of hematological diseases and disorders. However, most strategies target CD34+ cells, a heterogeneous mix of predominantly committed progenitors and only very few multipotent HSCs. Consequently, the HSC targeting efficiency is low, the long-term outcome poor and currently available approaches very costly.
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2018-02-05
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