Transcriptomic analysis of cspC deficient Acinetobacter baumannii

This study examined the response of A. baumannii to cspC disruption via transposon mutagenesis. The goal was to gain insight into how a cold shock protein highly expressed within A. baumannii biofilms, CspC, functioned and identify pathways in which it may be involved. Overall design: A. baumannii RNA was extracted to compare global gene expression of two samples: AB5075 wild type and AB5075 cspC transposon mutant. AB5075 wild type serves as the parental control strain. Each sample was generated by pooling three independent biological replicate RNA preps.