Transcriptional signatures that are down regulated by LeTx treatment and significantly rescued by MEK2cr.

aThe complete list of transcriptional signatures is presented in Table S1.
bt-statistics were obtained from three independent microarray experiments, and the scores in MEK1cr-expressing cells have p values greater than 0.005.
cMSigDB Gene Sets: http://www.broadinstitute.org/gsea/msigdb/search.jsp; GO (Gene Ontology): http://www.geneontology.org/; Cancer gene modules: http://robotics.stanford.edu/~erans/cancer/browse_by_modules.html.