DNA methylation landscape and signature of CD4+ lymphocytes of lamina propria in Crohn's patients by reduced representation and bisulfite sequencing [RNA-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE184307
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资源简介：
A genome-wide DNA methylation study was conducted using base resolution bisulfite sequencing for purified intestinal CD4+ cells (resected or biopsied mucosa of a terminal ileum) from 21 patients with Crohn’s disease and 12 age/sex matched controls. The sequencing data was analyzed for differentially methylated CpGs (DMCs) and differentially methylated regions (DMRs). Integration was performed with RNA-sequencing data for the same set of samples to verify the functional impact of DNA methylation changes. Crohn’s disease; CD4+ lymphocytes; DNA methylation; reduced representation bisulfite sequencing; differential methylation; Th17 phenotype; ATAC-sq Case/control study
创建时间：
2023-12-01
