The objectives of this investigation were to examine changes in the host transcriptional profiles during a Treponema denticola infection using a murine calvarial model of inflammation and bone resorpt
Endothelial cells (EC) are the main target for Orientia tsutsugamushi infection and EC dysfunction is a hallmark of severe scrub typhus in patients. However, the molecular basis of EC dysfunction and
Average normalized counts, log2-fold difference and false discovery rate (FDR) adjusted p-values were determined using DESeq2. Gene function was based on [9]. Functional categories were based on Gene