Pyrazolyl and Thienyl Aminohydantoins as Potent BACE1 Inhibitors
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Pyrazolyl and Thienyl Aminohydantoins as Potent BACE1 Inhibitors Descriptor: (5S)-2-amino-3-methyl-5-[3-(pyridin-3-yl)phenyl]-5-(thiophen-3-yl)-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 Authors: Chopra, R, Olland, A, Svenson, K. Deposit date: 2011-05-26 Release date: 2011-08-31 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: Exploring the S2' region. Bioorg.Med.Chem.Lett., 21, 2011
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2011-05-26
