Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions
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Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions Descriptor: 5-{4-[({[4-(5-carboxyfuran-2-yl)-2-chlorophenyl]carbonothioyl}amino)methyl]phenyl}-1-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit Authors: Feldkamp, M.D, Frank, A.O, Kennedy, J.P, Waterson, A.G, Olejniczak, E.T, Pelz, N.F, Patrone, J.D, Vangamudi, B, Camper, D.V, Rossanese, O.W, Fesik, S.W, Chazin, W.J. Deposit date: 2013-12-13 Release date: 2014-01-08 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. J. Med. Chem., 56, 2013
创建时间：
2013-12-13
