ChIP analysis of IRF1 in immortalized primary hepatocytes depleted of CSNK2B
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
Interferon regulatory factor 1 (IRF1) is a critical component of cell-intrinsic innate immunity that regulates both constitutive and induced antiviral defenses. However, how its activity is controlled by host factors has remained poorly characterized. We employed a ChIP-seq genome-wide investigation and revealed that CSNK2B plays important role in modulating IRF1 binding to DNA elements, thereby affecting transcription of cellular genes classified in diverse functional categories.
创建时间：
2022-09-28
