Oncogenic PI3K mutations lead to NF-kB-dependent cytokine expression following growth

ChEBI2012-04-30 更新2026-07-21 收录

PI3K信号通路

NF-kB炎症通路调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33403 数据链接链接失效反馈

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Oncogenic PI3K mutations lead to NF-kB-dependent cytokine expression following growth

创建时间：

2012-04-30

Deficiency of p110δ Isoform of the Phosphoinositide 3 Kinase Leads to Enhanced Resistance to Leishmania donovani

内脏利什曼病免疫机制

PI3K信号通路

Background Visceral leishmaniasis is the most clinically relevant and dangerous form of human leishmaniasis. Most traditional drugs for treatment of leishmaniasis are toxic, possess many adverse react

NIAID Data Ecosystem40

DataSheet3_Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice.DOCX

脓毒症心肌病分子机制

PI3K信号通路

Septic cardiomyopathy is the main complication and cause of death of severe sepsis with limited therapeutic strategy. However, the molecular mechanism of sepsis-induced cardiac injury remains unclear.

NIAID Data Ecosystem20

PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis

癌细胞耐药性

PI3K信号通路

PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis

ChEBI2011-09-13 更新10

Cardiac hypertrophy related to the phosphoinositide 3-kinase signaling pathway. Mus musculus

心脏肥大机制

PI3K信号通路

The insulin/IGF-IRS-PI3K-Akt pathway is highly conserved in evolution. To test whether this signaling cascade determines organ size in vertebrates, we have recently created mouse lines transgenic for

NIAID Data Ecosystem30

The Human Adenovirus E4-ORF1 Protein Subverts Discs Large 1 to Mediate Membrane Recruitment and Dysregulation of Phosphatidylinositol 3-Kinase

病毒-宿主相互作用

PI3K信号通路

Adenoviruses infect epithelial cells lining mucous membranes to cause acute diseases in people. They are also utilized as vectors for vaccination and for gene and cancer therapy, as well as tools to d

NIAID Data Ecosystem10

Oncogenic PI3K mutations lead to NF-kB-dependent cytokine expression following growth

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