Data of paraflocculus cochlear trauma and modulation of gene expression.
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Cochlear threshold dataSpreadsheet showing animal number (column A), treatment of each animal (column B) and cochlear threshold data. Cochlear threshold data are supplied as compound action potential (CAP) threshold values for frequency range 4 to 24 kHz in dB SPL determined ipsilaterally before treatment (Columns A-K), immediately after treatment (Columns L-V) and 2 weeks after treatment (Columns W-AG) as well as contralaterally 2 weeks after treatment (Columns AJ-AT).
RT-PCR DataSpreadsheet showing animal number (column A), treatment of each animal (column B) and replicate Ct values for gene of interest and for housekeeping genes ribosomal protein S16 (RPS16) and beta-2-microglobulin (B2M) (column E), from samples from left and right paraflocculus (PF). Columns C-H data for GABA-A receptor subunit alpha 1 (GABRA1); columns I-N data for glutamate decarboxylase 1 (GAD1); columns O-T data for glutamate receptor NMDA subunit 1 (GRIN1); columns U-Z data for a member of RAB family of small GTPase (RAB3A).
耳蜗阈值数据表格,展示了动物编号(列A)、每只动物的处置方法(列B)以及耳蜗阈值数据。耳蜗阈值数据以复合动作电位(CAP)阈值值的形式提供,涵盖4至24 kHz的频率范围,以分贝声压级(dB SPL)为单位,在治疗前后分别从同侧(列A-K)、治疗即刻(列L-V)和治疗2周后(列W-AG)以及对侧2周后(列AJ-AT)进行测定。RT-PCR数据表格,展示了动物编号(列A)、每只动物的处置方法(列B)以及针对目标基因(如:核糖体蛋白S16(RPS16)和β-2-微球蛋白(B2M))以及内参基因(如:GABA-A受体亚基α1(GABRA1)、谷氨酸脱羧酶1(GAD1)、NMDA型谷氨酸受体亚基1(GRIN1)和RAB家族小GTPase成员(RAB3A)的复制Ct值,数据来自左右副海马(PF)的样本。列C-H的数据对应于GABA-A受体亚基α1(GABRA1);列I-N的数据对应于谷氨酸脱羧酶1(GAD1);列O-T的数据对应于NMDA型谷氨酸受体亚基1(GRIN1);列U-Z的数据对应于RAB家族小GTPase成员(RAB3A)。
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