Correlation between injecting networks and HCV phylogeny.

Notes:HCV: hepatitis C virus; MCL: maximum composite likelihood.1Baseline refers to the baseline injecting network: nodes are participants that were recruited in the main recruitment waves at the beginning of the study; edges are injecting relationships reported in those participants' first interviews. The network is undirected. Flattened refers to the flattened injecting network: nodes are participants recruited up to August 2008; edges are injecting relationships reported during this period. The network is undirected.2Geodesic distances calculated using complete baseline and flattened networks. Correlations between geodesic distances and MCL distances calculated for the subgroup of participants indicated.3Adjusted Jaccard coefficients provided for association between binary injecting networks and phylogenetic clusters. QAP analysis for adjusted Jaccard coefficients conducted in UCINET, 12500 permutations. Tau c coefficients provided for correlation between geodesic injecting network distances and MCL genetic distances. QAP analysis for tau c coefficients conducted in STATA, 5000 permutations. Statistical significance defined as pmaterials and methods section.4The p-value is based on the percentile of the empirical sampling distribution generated by the QAP in which the observed test statistic falls.5The mean and standard deviation of the test statistic in the empirical sampling distribution.Statistically significant results are presented in italics.