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Structure of the FKBP51FK1 domain in complex with the macrocyclic SAFit analogue 56

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Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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Structure of the FKBP51FK1 domain in complex with the macrocyclic SAFit analogue 56 Descriptor: (2S,9S,12R)-2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-24,27-dimethoxy-11,18,22-trioxa-4-azatetracyclo[21.2.2.113,17.04,9]octacosa-1(25),13(28),14,16,23,26-hexaene-3,10-dione, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Bauder, M, Meyners, C, Purder, P, Merz, S, Voll, A, Heymann, T, Hausch, F. Deposit date: 2020-08-27 Release date: 2021-03-17 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors. J.Med.Chem., 64, 2021

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2020-08-27
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